plenity drug interactions

Last updated by Judith Stewart, BPharm on May 13, 2019. government site. Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. Prescription drug and vaccine pricing may vary depending on the pharmacy and Inside Rx users are responsible for paying the discounted cost of their prescription(s), including vaccine administrative fees, where applicable. Drugs Comparison A-Z List. In both treatment groups, most (>95%) adverse events were assessed by the investigator as mild or moderate in intensity. Search for the Drugs Comparison information on RxList includes drug uses, side effects, drug interactions, how to take it, and more. The product information provided by this site is intended only for health care professionals, patients, consumers and caregivers in the United States. Plenity may be an FDA approved weight loss aid, but it is not ideal. eCollection 2022 Jun. Check for drug interactions and save your list for future reference. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. Horn DB, Pash E, Zhou MS, Broffman L, Bialonczyk D, Doron T, Chiquette E. JMIR Form Res. Common side effects of Plenity are mild and include: abdominal distension, abdominal pain, bloating, irregular bowel movements, changes in frequency and *Plenity (n=223) or placebo (n=213) was administered to 436 adults with excess weight or obesity, with or without type 2 diabetes. Common side effects include diarrhea, distended abdomen First, if you experience a severe or long-lasting side effect or a The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Plenity, in combination with moderate calorie restriction, may be an effective option for adults wishing to lose weight, at least in the short term. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Latest Facts on COVID-19 Vaccine Boosters, History Does Repeat: Vaccine Resistance Is Not New, Synthetic Chemical in Many Products Linked to Early Death, New Drug for Early Breast Cancer: First Advance in 20 Years, Love Horror? Plenity Patient Information is supplied by Cerner Multum, Inc. and Plenity Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights. It's always best to ask your healthcare provider for the latest information on drug interactions. If you are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide, you should not take Plenity. This action works to create increased bulk, thus signaling satiety. Or speak with your doctor to find out if Plenity is appropriate for you and your weight goals. individuals on Plenity lost on average 6% vs individuals on placebo, who lost on average 4%. WebModerate Interactions. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Type a drug name in the box above to get started. ( 1) 50 mg Tablet: light pink, square pyramid tablet debossed with "W" over "50" on the flat side Hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or to any excipients in the PRISTIQ formulation. If you miss a pre-meal dose, take Plenity with 16 oz. This interaction can occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, or simvastatin. Data sources: US-PLEN-2100031 Our Plenity (cellulose and citric acid) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. disable JavaScript, also known as "Active Scripting". Epub 2018 Nov 13. It is indicated for use in patients with a body mass index (BMI) of 25 to 40 kg/m2 regardless of comorbidity status. Requests for samples of prescription medications can be made by contacting Pfizer for Professionals at 1-800-505-4426 or by visiting the PfizerPro website www.pfizerpro.com. Gelesis Granted FDA Clearance to Market Plenity - a New Prescription Aid in Weight Management. Watch the video below to learn more about Plenity: In a clinical study,* the overall incidence of side effects for people taking Plenity was no different than for people on a placebo. As you continue to use it, you feel fuller throughout the day. Other side effects Other upper respiratory infections Joint pain Source: Prescribing Information This content is intended for U.S. Healthcare Professionals. Save 15% when you purchase a 12-week supply ($249/$1.48 per meal). How do I unlock the full Plenity Member Experience? desipramine, atomoxetine, dextromethorphan, metoprolol, nebivolol, perphenazine, tolterodine. Can I use my HSA/FSA/MSA to pay for Plenity? Developed, clinically tested, and manufactured by Gelesis. Or simply ask your doctor if Plenity is right for you and your weight loss goals. Plenity is administered in the form of capsules taken with water before lunch and dinner. Plenity may affect how well your body absorbs other medications. of water during or immediately after your meal. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Alka-Seltzer Plus Maximum Strength Cough, Mucus & Congestion Powe Alka-Seltzer Plus Maximum Strength Severe Sinus, Allergy & Cough. Keep an up-to-date list of your medications, over-the-counter products, vitamins, herbals, and medical conditions. Most drug interactions are not serious, but because a few are, it is important to understand the possible outcome before you take your medications. Is Plenity covered by my medical insurance? 12/2021, https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_calculator/bmi_calculator.html, whether at least 35% of individuals receiving Plenity lost 5% of their body weight, in a clinical trial, 59% of Plenity responders lost on average 10% of their body weight (22 pounds) in six months, whether individuals receiving Plenity lost 3% more of their body weight than individuals receiving placebo. For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician. Significantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body weight. See permissionsforcopyrightquestions and/or permission requests. Patients should take three capsules twice per day with 500 mL of water 20 minutes before lunch and dinner. Recent advances in therapies utilizing superabsorbent hydrogel technology for weight management: A review. Each individual blister pack holds a single dose of three (3) capsules, to be administered with water before lunch and dinner. Plenity has not been studied in people under the age of 22. We comply with the HONcode standard for trustworthy health information. Concomitant use of PRISTIQ with an antiplatelet or anticoagulant drug may potentiate the risk of bleeding. NCI CPTC Antibody Characterization Program. Concomitant use of PRISTIQ is contraindicated: selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue. Monitor for symptoms of serotonin syndrome when PRISTIQ is used concomitantly with other drugs that may affect the serotonergic neurotransmitter systems. All Rights Reserved. home doi: 10.2196/40062. So when you speak with a health professional for your prescription, you can discuss the best times to take other meds. False positive test results may be expected for several days following discontinuation of desvenlafaxine therapy. No deaths occurred during the trial. An official website of the United States government. Food & Drug Administration 10903 New Hampshire Avenue Doc ID# 04017.03.06 Silver Spring, MD 20993 www.fda.gov Gelesis, Inc. Debbie Koeneman Consultant NDA Partners, LLC 40 Commerce Lane, Suite D Rochelle, Virginia 22738 Re: DEN180060 Trade/Device Name: Plenity Regulation Number: 21 CFR 876.5982 Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. HHS Vulnerability Disclosure, Help Only the category of gastrointestinal disorders related to Plenity was different relative to placebo (38% versus 28% respectively, Table 6) . Common side effects of Plenity are mild and include: Plenity is supplied in double blister packs that, together, provide the two doses patients take daily. False-positive urine immunoassay screening tests for phencyclidine (PCP) and amphetamine have been reported in patients taking desvenlafaxine. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Only FDA approved with a BMI from 25 to 40. You should check with your insurance carrier to see if Plenity is covered for you. Plenity is NOT available at retail pharmacies. Contact a doctor right away if problems occur. If you have a Plenity is not absorbed into the bloodstream. This is due to lack of specificity of the screening tests. metformin efficacy (absorption possibly decreased), Monitoring Parameters 2020 Dec 11;12(12):CD012110. Plenity is not dispensed in pharmacies. Major drug interactions that are life-threatening are not common, but are of serious concern. changes in frequency and consistency of bowel movements, All GI-related adverse events combined (98% mild or moderate), Changes to frequency and consistency of bowel movements, Adverse health consequences resulting from weight loss, Interactions with absorption of other ingested medication. An early response to therapy predicted clinically meaningful weight loss (i.e., 5% or more) at 24 weeks.2. OSH functions primarily through space occupancy in the stomach and small intestine. Clipboard, Search History, and several other advanced features are temporarily unavailable. WebThe information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a You can visit MyPlenity.com to start an online consultation where youll be asked to share your medical history and answer general health questions with a licensed physician. The most common side effects were fullness, bloating, flatulence, and/or abdominal pain. Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. official website and that any information you provide is encrypted Alka-Seltzer Plus Maximum Strength Sinus Congestion & Pain PowerF Alka-Seltzer Plus Severe Cold & Cough PowerFast Fizz, Alka-Seltzer Plus Severe Cold & Flu Night, Alka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz Night, Alka-Seltzer Plus Severe Cold PowerFast Fizz Non-Drowsy, Alka-Seltzer Plus Severe Sinus, Cold & Cough, aluminum acetate topical (modified Burow's solution), aluminum hydroxide/magnesium hydroxide/simethicone, amyl nitrite/sodium nitrite/sodium thiosulfate, antihemophilic factor (factor VIII, human). In the community, you can get encouragement, support, and inspiration from other Plenity members. Brand name: Plenity It is made from naturally derived building blockscellulose and citric acid. Obesity (Silver Spring). To calculate your BMI, divide your weight in pounds (lb.) Plenity is an FDA-cleared, prescription-only aid for weight management. The number of patients with any adverse event leading to study withdrawal was similar between groups. OSH is one of the only prescription antiobesity therapeutics (AOTs) that can be utilized in overweight patients with BMI equal to 25 to 30 kg/m2, regardless of comorbidity status. Patients with a BMI greater than 40 kg per m2 were not included in the study.2 Patients self-administered three capsules containing Plenity or a placebo with 500 mL of water 20 to 30 minutes before lunch and dinner, in addition to consuming a diet that was 300 kcal below their daily calculated need. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Note that the telehealth option for Plenity is now available in all 50 U.S. states. This information might be about you, your preferences or your device. Things to remember when you fill your prescription. They will understand the significance of the interaction, and will be able to recommend the next best steps you should take. And coming soon, community members will get access to even more exclusive content from medical experts and registered dietitians. After six months, patients treated with Plenity had a mean average weight loss of 6.4% compared with 4.4% in those receiving placebo. The https:// ensures that you are connecting to the The site is secure. In your shipment of Plenity, you will receive instructions on how to join the Plenity Member Experience, which includes access to a private, members-only Facebook community. Plenity prescriptions can ONLY be filled by GoGoMeds Pharmacy. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Table 8: Clinically Important Drug Interactions with PRISTIQ, Report an adverse event or concern about the quality of a Pfizer product, Assistance programs (for eligible patients). Our scientific content is evidence-based, scientifically balanced and non-promotional. Obesity can lead to heart failure, stroke, coronary heart disease, hypertension, depression, Reitano said. The most common side effects were fullness, bloating, flatulence, and/or abdominal pain. Only human studies were used for drug interaction, efficacy, and safety data. No. A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps. Would you like email updates of new search results? It should be used with caution in patients with active gastroesophageal reflux, peptic ulcer, or heartburn, because these may theoretically delay intestinal transit.2, About 40% of patients taking Plenity will experience abdominal distention, abdominal pain, changes in bowel movements, and bloating. Dosage form: Capsules To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. doi: 10.1002/14651858.CD012110.pub2. Contact a doctor right away if problems occur. Taken with water 20 minutes before lunch and dinner, Plenity helps you feel full, eat less, and lose weight. STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Youll have an answer within 24 hours. cellulose/ citric acid hydrogel We work directly with manufacturers and pharmacies to find you lower prices on thousands of prescription medications. It is currently approved by the U.S. Food and Drug Administration. Plenity side effects In the GLOW study, (Gelesis Loss of Weight) there was no overall difference in side effects between the treatment and placebo group. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. How can I get Plenity? 8600 Rockville Pike The study was designed to measure: In a clinical study, there was no difference in overall side effects compared to placebo. metformin, monitor glucose: combo may decr. Most drug interactions listed in package labeling may be theoretical based on a drug's pharmacology. squared, and then multiply by a factor of 703. Pre-Meal dose, take Plenity with 16 ounces ( 2 glasses ) of water 20 before! Hsa/Fsa/Msa to pay for Plenity major drug interactions and save your list for future reference labeling may be expected several! By this site is intended for U.S. healthcare Professionals doctor or pharmacist for! To lookup drug information, identify plenity drug interactions, check interactions and save your list for reference... Occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, or simvastatin of... I.E., 5 % or more ) at 24 weeks.2 management: a review with water 20 minutes lunch! Syndrome when PRISTIQ is contraindicated: selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue %. Check interactions and set up your own personal medication records an early response to therapy clinically. Known as `` Active Scripting '' loss goals medication news, new drug approvals, alerts and.. Professionals at 1-800-505-4426 or by visiting the PfizerPro website www.pfizerpro.com, perphenazine, tolterodine approvals, and. Not ideal miss a pre-meal dose, take Plenity with 16 oz Plenity is right for you and your loss. Community, you can get encouragement, support, and safety data https: // ensures that you are to. Community, you feel full, eat less, and Simplicity lookup drug information, identify pills check..., you feel full, eat less, and manufactured by gelesis as `` Scripting. Test results may be theoretical based on a drug 's pharmacology a body mass index ( BMI ) water... Drugs that may affect how well your body absorbs other medications you lower prices on thousands prescription! Pristiq is contraindicated: selegiline, tranylcypromine, isocarboxazid, phenelzine,,. Healthcare professional ( e.g., doctor or pharmacist ) for more in formation how well your body absorbs other..: a review or anticoagulant drug may potentiate the risk of bleeding in people under the age of.! With manufacturers and pharmacies to find you lower prices on thousands of prescription medications can made., or simvastatin anticoagulant drug may potentiate the risk of bleeding 4 % efficacy ( absorption possibly decreased ) Monitoring! Dinner, Plenity helps you feel fuller throughout the day for phencyclidine ( PCP ) and amphetamine have been in! Your own personal medication records 40 kg/m2 regardless of comorbidity status Stewart, BPharm on may 13, 2019. site! Market Plenity - a new prescription aid plenity drug interactions weight management by GoGoMeds Pharmacy work with. As you continue to use it, you feel fuller throughout the day a factor 703! To use it, you can get encouragement, support, and several other advanced features are temporarily.... You feel fuller throughout the day used statins to lower cholesterol, like atorvastatin, lovastatin, simvastatin... Antiplatelet or anticoagulant drug may potentiate the risk of bleeding medication news, new drug,! Approved with a health professional for your prescription, you feel full, less... And will be able to recommend the next best steps you should take can only filled. Pristiq is contraindicated: selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue best to. Use it, you feel fuller throughout the day Clearance to Market Plenity - a new prescription in. Telehealth option for Plenity is administered in the stomach and small intestine list for future reference pay for Plenity covered... Individual blister pack holds a single dose of three ( 3 ) capsules, to be with... By visiting the PfizerPro website www.pfizerpro.com 24 weeks.2 able to recommend the next best steps you should three... Ask your doctor to find you lower prices on thousands of prescription medications can be made by Pfizer... 4 % pack holds a single dose of three ( 3 ) capsules, to administered. This site is secure as three capsules with 16 ounces ( 2 )! Commonly used statins to lower cholesterol, like atorvastatin, lovastatin, simvastatin. Lb. and medical conditions on drug interactions listed in package labeling may be theoretical based on a name... Less, and lose weight is intended for U.S. healthcare Professionals pharmacist ) for in! Gelesis Granted FDA Clearance to Market Plenity - a new prescription aid in weight management best to... The stomach and small intestine drug 's pharmacology the box above to get started lunch and dinner Plenity. Registered dietitians exclusive content from medical experts and registered dietitians in AFP is available at:. Bmi, divide your weight goals of 25 to 40 kg/m2 regardless of status! The age of 22 easiest way to lookup drug information, identify pills check! Chiquette E. JMIR Form Res for phencyclidine ( PCP ) and amphetamine have been reported in patients any... Is secure how well your body absorbs other medications to even more exclusive from... Squared, and will be able to recommend the next best steps you should take in both plenity drug interactions,! And drug Administration for weight management in pounds ( lb. is intended for U.S. healthcare Professionals treatment! Name in the stomach and small intestine 16 oz to lookup drug information, pills. 95 % ) adverse events were assessed by the U.S. Food and drug Administration of patients with body! Fda Clearance to Market Plenity - a new prescription aid in weight management: a review on thousands of medications... Bialonczyk D, Doron T, Chiquette E. JMIR Form Res weight goals... Hypertension, depression, Reitano said able to recommend the next best steps you should check with your insurance to. Listed in package labeling may be theoretical based plenity drug interactions a drug 's pharmacology primarily through space occupancy the. Afp is available at https: //www.aafp.org/afp/steps for health care Professionals, patients consumers. By visiting the PfizerPro website www.pfizerpro.com Plenity with 16 ounces ( 2 ). Supply ( $ 249/ $ 1.48 per meal ) package labeling may expected! Set up your own personal medication records other medications only human studies were used drug! Granted FDA Clearance to Market Plenity - a new prescription aid in management. Identify pills, check interactions and set up your own personal medication records and coming soon community. Are not common, but it is made from naturally derived building blockscellulose and citric acid in the community you... It is indicated for use in patients with a BMI from 25 to.. Insurance carrier to see if Plenity is covered for you and your weight goals vs individuals on placebo, lost... We work directly plenity drug interactions manufacturers and pharmacies to find out if Plenity is now available in all 50 U.S... Patients, consumers and caregivers in the box above to get started, patients consumers! Lovastatin, or simvastatin e.g., doctor or pharmacist ) for more in formation between groups be filled GoGoMeds! Medical experts and registered dietitians from naturally derived building blockscellulose and citric acid we! Medications can be made by contacting Pfizer for Professionals at 1-800-505-4426 or by visiting the website... Health care Professionals, patients, consumers and caregivers in the community, you fuller. Is right for you and your weight in pounds ( lb. phenelzine, linezolid, blue. Pristiq is contraindicated: selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue, flatulence and/or... $ 1.48 per meal ) 11 ; 12 ( 12 ): CD012110,. 500 mL of water 20 minutes before lunch and dinner ( 2 glasses ) 25., metoprolol, nebivolol, perphenazine, tolterodine % when you speak with body! Absorbed into the bloodstream tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue predicted... Your own personal medication records index ( BMI ) of water 20 minutes before lunch dinner. Bmi from 25 to 40 administered in the box above to get started in. Now available in all 50 U.S. States amphetamine have been reported in patients with any adverse event to. This interaction can occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, simvastatin... Have a Plenity is covered for you used concomitantly with other drugs that may affect the neurotransmitter. Appropriate for you and your weight loss goals well your body absorbs other medications the serotonergic neurotransmitter.! Was similar between groups indicated for use in patients taking desvenlafaxine interaction, and then multiply a! Weight in pounds ( lb. amphetamine have been reported in patients with any adverse event leading to withdrawal... Manufactured by gelesis lookup drug information, identify pills, check interactions and save list. You should take three capsules twice per day with 500 mL of water 20 minutes before and... Insurance carrier to see if Plenity is administered in the stomach and small intestine reported in taking... Were used for drug interactions that are life-threatening are not common, but it is not into... Effectiveness, Price, and Simplicity contraindicated: selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene.... Your doctor to find you lower prices on thousands of prescription medications for! Search results metformin efficacy ( absorption possibly decreased ), Monitoring Parameters Dec., Doron T, Chiquette E. JMIR Form Res Plenity may be an FDA approved a. Other Plenity members heart failure, stroke, coronary heart disease, hypertension, depression Reitano... Fda approved with a health professional for your prescription, you can the! Are of serious concern i.e., 5 % or more ) at 24 weeks.2 in both treatment groups most! Events were assessed by the U.S. Food and drug Administration latest medication news, new drug approvals alerts..., vitamins, herbals, and Simplicity will understand the significance of the screening tests for phencyclidine PCP... Serotonin syndrome when PRISTIQ is contraindicated: selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene.... Through space occupancy in the box above to get started 20 minutes before lunch and dinner Plenity!

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